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Toxicology

Practice Exam Questions - Bank 4

1. Relative to inhalation toxicity, oral toxicity is generally: (Plog, 125)
a. higher
b. about the same
c. the same
d. lower
2. For a given substance, oral toxicity is generally _____ inhalation toxicity: (Plog, 125)
a. higher than
b. about the same as
c. the same as
d. lower than
3. This is an important systemic defense process to reduce the toxic effects of a chemical: (Plog, 126)
a. lymphatic system
b. remuneration
c. detoxification
d. deterioration
4. All of the following occur as part of the body's detoxification process, EXCEPT: (Plog, 126)
a. the liver degrades the toxin
b. the toxin is converted to a non-toxic water-soluble compound
c. attack by macrophages
d. transportation to kidneys and excreted
5. Which of the following is not an area into which a toxic substance may be injected? (Plog, 126)
a. the bloodstream
b. the duodenal sac
c. the peritoneal cavity
d. the pleural cavity
6. There is increased attention to prevention of skin puncture and injection injuries due to all of the following bloodborne pathogens, EXCEPT: (Plog, 126)
a. pneumococcus
b. HIV
c. hepatitis C
d. hepatitis B
7. All toxicological considerations are based on the: (Plog, 126)
a. dosage-toxic constant
b. dose-response relationship
c. toxic-absorption constant
d. toxicological relationship
8. What is the point on a dose-response curve in which a lethal response occurs to half of the animals administered a chemical agent? (Plog, 126)
a. LD0
b. LD5.0
c. LD50
d. LD100
9. Which of the following are the two variables used to determine the dose-response relationship? (Plog, 126)
a. concentration (C) and frequency (F) of exposure
b. temperature (T) and duration (D) of exposure
c. duration (D) and frequency (F) of exposure
d. concentration (C) and duration (T) of exposure
10. Regulatory exposure limits are set such that these two variables are theoretically below levels that produce injury: (Plog, 126)
a. concentration (C) and frequency (F) of exposure
b. temperature (T) and duration (D) of exposure
c. duration (D) and frequency (F) of exposure
d. concentration (C) and duration (T) of exposure

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